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Recommendations when to order or not order the test. May include related or preferred tests.
Use to detect and subtype protein S deficiency. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Serum. EDTA plasma, clotted or hemolyzed specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months
Methodology
Process(es) used to perform the test.
Microlatex Particle-Mediated Immunoassay
Performed
Days of the week the test is performed.
Mon-Sat
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
1-4 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
1-89 days: 15-55% 90-179 days: 35-92% 180-364 days: 45-115% 1-5 years: 62-120% 6-9 years: 62-130% 10-17 years: 60-140% 18 years and older Male: 74-147% 18 years and older Female: 55-123%
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Refer to report
Compliance Category
FDA
Note
Additional information related to the test.
If low Protein S Free Antigen is detected, then Protein S, Total Antigen, will be added. Additional charges apply.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
Protein S Profile
Protein S, Free and Total Antigen
Protein S, Free Antigen with Reflex to Protein S, Total Antigen